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1-Isothiocyanato-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker.
Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Cyclopropylmethyl bromide is an intermediate Cyclopropylmethyl bromide can be used in the preparation of Firocoxib (HY-14670) Firocoxib (ML 1785713) is a potent selective orally active COX-2 inhibitor[1]
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Diallyl disulfide is an organosulfur compound derived from garlic oil and supplied as a research-grade analytical standard. It is used in biochemical and pharmacological research and has been reported to act as a squalene monooxygenase inhibitor. Typical chemical identifiers include CAS 2179-57-9, molecular formula C6H10S2, molecular weight 146.27 g·mol⁻¹, and a manufacturer-stated purity of approximately 99.3%.
High purity suitable for analytical applications.
Verified identity with CAS and molecular data.
Available in small pack sizes for laboratory use.
Useful as a biochemical probe in enzymatic studies.
Liquid form for straightforward handling and storage.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Benzcyclane (Benzcyclan) is an inhibitor of platelet aggregation and also a vasodilator that can be used in a variety of peripheral circulation disorders. purity: 99%
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Allyl methyl sulfide (CAS No 10152-76-8) is an organosulfur compound primarily studied in biomedical research for its bioactive properties Originating from garlic it is known for its potential antioxidant and antimicrobial activities The compound acts by modulating oxidative stress pathways and inhibiting microbial growth potentially impacting cellular signaling processes In vitro it exhibits activity in the nanomolar to low micromolar range showcasing its potency across various experimental conditions Common applications include studies involving cell lines and animal models to explore its therapeutic potential and utility in drug screening assays Experimental concentrations typically depend on the specific research design allowing for flexibility in diverse investigative contexts
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Allyl Methyl Sulfide (3-Methylthio-1-propene) a bioactive organosulfur compound found in garlic is reported to modulate disease states such as cancer and infection
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Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide which is a highly reactive metabolite and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis Thioacetamide can induce chronic liver fibrosis encephalopathy and other events model[1][2][3][4]
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Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration Thioacetamide can be used to induce animal models of Cirrhosis
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Sodium Sulfadiazine (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine an intermediate-acting bacteriostatic synthetic sulfanilamide derivative
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